LİSANS DERS İÇERİKLERİ


BIO111 General Biology-I (3-0-0)

Cellular basis of life; Chemical basis of plant and animal cell structure and functions; structure and function of cell membrane; Cellular energy production: photosynthesis, cellular respiration; Control of cellular activities; Cell reproduction; Genetic basis of life.

BIO112 General Biology-II (3-0-3)

Fundamentals of the evolution of organisms; Natural selection theory and the mechanism of evolution; Diversity of life and its classification; Structure and function in organism level; Behaviour of organisms in biological and physical environment; Basic concepts of ecology.

BIO 211E Cell Biology (3-0-3)

Molecular level analysis of cellular structure and function; Recent developments in cellular energetics; Cytoskeleton ve cellular movement; Cell cycle and division; Intracellular recognition and cellular adhesion; Cell to cell trafficking and chemical signalling in cell differentiation.

BIO 221 Ecology (3-0-0)

Interactions of organisms with their biological and physical environment; ecosystem concept; environmental requirements of organisms; limiting factors; Energy circulation in ecosystems; biogeochemical cycles; Fundamentals of population ecology and community ecology, plant entomology.

BIO 212 Genetics (3-0-0)

Basic concepts of Mendelian genetics; Chromosome theory in heredity; Structure and function of genes; Gene expression and its regulation; Mutations and chromosomal defects; Development, behaviour and population genetics and basic principles of evolutional genetics.

BIO 222 Systematic biology      (2-0-0)

A general view of diversity of biosphere; Species and speciation; Definitions and concepts of contemporary taxonomy; phylogeny, homology and analogy; Fenetic and cladistic approaches of taxonomy; Systematics of Bacteria, Fungi, Protista, Plantae and Animalia.

BIO 311 Biochemistry-I (3-0-0)

Life and molecules, amino acids, protein structure and function, Enzymes and the basis of enzyme kinetics, enzymatic catalysis mechanisms, carbohydrates, lipids, nucleic acids, structure and functions of membranes, DNA as genetic material, DNA replication, transcription, translation and regulation of gene expression.

BIO 312 Biochemistry-II (3-0-3)

The catabolism of phosphate bond energy, Glycolysis, tricarboxylic acid cycle, pentose phosphate pathway, oxidative phosphorilation, oxidation of fatty acids, oxidative degeneration of amino acids, photosynthesis, biosynthesis of carbohydrates, lipids, amino acids and nucleotides.

BIO 321 Microbiology (3-0-3)

Structure of microorganisms (bacteria, yeast, fungi and viruses), functions, bacterial and viral growth, classification, physiology, metabolism and genetics, identification and control of microorganisms, microorganism-environment interactions, microbial pathogenesis and immunology, human-microorganism interactions.

BIO 331E Molecular Genetics (2-0-3)

Structure of genes, replication, molecular basis of transcription and translation, recombination at molecular level, Mutation and DNA repair, molecular basis of protein synthesis, regulation of gene function in bacteria, organization of eukaryotic genomes and regulation of expression, transposons, phage genetics, gene cloning and manipulation, molecular genetics of development, cancer at molecular level.

BIO 332E Modern Techniques in Biology (3-0-0)

Light and electron microscopy, Spectroscopic techniques in biology, circular dichroism, the principles of chromatography, protein purification using chromatographic techniques, electrophoretic methods, identification of proteins and nucleic acids by electrophoresis, radioactive labelling methods, membrane filtration and dialysis techniques, centrifugation methods.

BIO 471 Modern Techniques in Molecular Biology (3-0-0)

Western blot of proteins, determination protein/peptide sequences, immuno-electrophoresis methods, ELISA, ligand binding methods, nucleic acid hybridization methods, autoradiographic methods, immunological methods, immunoprecipitation and radioimmunoassays, Southern and Northern blot techniques, electroporation, nucleic acid purification techniques, DNA sequencing techniques.

BIO 322 Physiology (3-0-0)

Biological control systems, homeostatic mechanisms and cellular trafficking (membrane transport, transport mechanisms), neural control mechanisms (membrane potential, diffusion), central nervous system, hormonal control mechanisms, skeletal muscle system; coordinated body functions, blood circulation systems, respiration, kidneys, digestive system, growth and reproduction, body’s defence mechanisms.

BIO 351 Biophysics (3-0-0)

Microscopic and sub-microscopic methods in analysis of biological structures and functions; Medical scanning techniques; Radiation biophysics; Molecular organizations and dynamics of membranes; Thermodynamic principals of life processes; Biophysics of neural system and neuronal tranduction.

BIO 411 Molecular Biology (4-0-3)

Structures of biological macromolecules, their synthesis, basic genetic mechanisms, control of gene expression, mobile DNA elements, control of DNA replication, plasmids, genetics of viral groups, basis of genetic engineering, control of cell division, cell to cell adhesion, chemical signals between the cells, embryonic cells and fertilization, cellular mechanisms of development, cell differentiation, protection of tissues, molecular biology of the immune system.

BIO 341 General Biotechnology (3-0-0)

Cell production methods in biotechnological processes; Cytochiometry of microbial reproduction and material production; Basis of fermentation technology; Fundamentals of enzyme engineering; Purification and recovery techniques of biomolecules; Classification, operation and control of bioreactors; Mixed cultures; Utilization of genetically modified microorganisms; Material production by plant cell cultures; Material production by animal cell cultures.

BIO 412E Recombinant DNA Techniques (3-0-0)

Basic methods in gene manupilation; cutting and joining DNA molecules; gene cloning methods in bacteria other  than Escherichia coli; cloning in Saccharomyces cerevisiae and other microbial eukaryotes; gene transfer to plant and animal cells; modification and mutagenesis; polymerase chain reaction; applications of recombinant DNA technology; making transgenic plants; producing transgenic animals; recombinant DNA technology and medicine; genetic mapping.

BIO 461E Microbial Growth Kinetics (3-0-0)

Batch growth kinetics, the effect of environmental conditions on growth kinetics, heat generation during microbial growth, continuous cultivation techniques: chemostat and turbidostat, growth kinetics in continuous culture, fed-batch cultivation kinetics, growth and product yields in microbial growth kinetics, models describing growth kinetics, mixed cultures and simple models describing mixed cultures.

BIO 451E Industrial Microbiology (3-0-0)

Industrial microorganisms, preservation techniques for industrial microorganisms, the isolation of industrially important microorganisms from natural resources, chemical mutations and improvement of microorganisms using genetic engineering techniques, biomass and biofuel production, microbial production of enzymes, antibiotics, aminoacids and organic acids by fermentation processes. The use of microorganisms in food production processes,

BIO 432E Microbial Physiology (3-0-0)

The organization and chemical structure of microorganisms, microbial organelles and their functions, metabolism and synthesis mechanisms of microbial polymeric structures, anabolic and catabolic metabolism of microorganisms, nitrogen, sulfur and phosphorus assimilations, physiology of microbial growth, environmental effects on microbial growth, control of genetic mechanisms and gene expression in microorganisms, coordination of metabolic reactions in microorganisms.

BIO 342E Enzymology (3-0-0)

Biology and chemistry of enzymes, laboratory and industrial techniques of enzyme purification, kinetics of enzymatic reactions: rapid equilibrium and steady-state kinetics, reversible and irreversible inactivation kinetics, enzymatic catalysis mechanisms, mechanisms to regulate enzyme activity, allosteric enzymes, industrial use of enzymes and enzyme immobilization methods, enzyme stabilization methods.

BIO 472 Plant Physiology (3-0-0)

Plant morphology, fundamentals of plant physiology. Plant structure, photosynthesis, respiration and bioenergetics, mineral supply in plants, water relations, productivity, growth and differentiation, functional anatomy and physiology involving transport phenomena, plant stress physiology and energy flow: protein and lipid metabolism under abiotic stress conditions, plant hormones and their effects on plant growth.

BIO 482 Transgenic Plant Technology (3-0-0)

Gene cloning in plants; Transferring genes into plants Ti-plasmid vectors; tissue-specific expression of transferred genes in plants; improving transgenic plants by gene transfer techniques; basic methods in plant biotechnology.

BIO 442 Molecular Immunology (3-0-0)

Characteristics of ımmun response in molecular, cellular and organism level; chemical structures and functions of antigens and immunoglobulins; cellular and humoral immunity; immunodeficiency disease; otoimmunity; blood group systems; transplantation.

BIO 452 Virology (3-0-0)

Important viruses in animals and plants; structure, morphology, classification and genetics of viruses; virus-host cell relation and viral etiology of cancer; molecular biology of viruses.

BIO 422E Mathematical Biology (3-0-0)

General mathematic principles in biology,  applications of dynamic systems in biology: mathematical theory of enzyme kinetic, biochemical system analysis, biochemical oscillations; Lotka-Volterra models; applications of transportation and diffusion equations; Pheromones, genetic drift; diffusion problem in biology,  linear and non-linear dynamic systems in biology; stability in dynamic systems; introduction to non-otonomous systems;  dynamic directions of morphogenesis.

BIO 421E Transport Phenomena (3-0-0)

Momentum transfer (introduction to biorheology, flow behavior in suspended environment, flow in channels, macroscopic mass, momentum and energy balances); mass transfer (mass and energy transfer in multicomponent systems, diffusion in free solutions, mass transfer against biologic membranes and biomolecular lipid models)

BIO 462E Protein Structure-Function Relationships (3-0-0)

Primary, secondary, tertiary and quaternary protein structures; General principals in protein folding pathways; thermodynamics and kinetics of protein folding; Chaperons; Estimation methods of secondary structures from amino acid sequence, Probability methods, statistical mechanic-based methods; Functions seen in protein molecules; Studies of ligand binding in proteins; Chemical modifications of proteins and reciprocal binding; Protein modifications with directed-mutagenesis (protein engineering).

BIO 431 Open System Thermodynamics (3-0-0)

Conservation of energy and open systems, First and second law of thermodynamics; Linear irreversible thermodynamics; Rates of irreversible processes and entropy production; Non-linear thermodynamics of  irreversible systems.

BIO 441 Separation Methods in Biology (3-0-0)

Characteristics of biological separation methods, characteristics of biological materials; Filtration, microfiltration and reciprocal flow filtration techniques, centrifugation techniques; Extraction methods in biological systems; Separation processes  using adsorption technique; Chromatographic techniques; Precipitation techniques with salts and organic solvents; Ultrafiltration and electrophoresis.

BIO 491 Molecular Biotechnology (3-0-0)

Determination of gene sequences; Polymerase chain reaction technology; Production of monoclonal antibody technology; Industrial and pharmaceutical applications in microorganism host systems; Basic principals of gene therapy in animals and human.

 
BIO 471E Protein Biotechnology (3-0-0)

Protein sources; Steps in obtaining protein products from native environments; Therapeutic proteins: Blood products, vaccines, monoclonal antibodies, hormones; Protein-based metabolic regulators; Proteins aiming
diagnosis; Enzymes hydrolyzing polymers and their applications; other proteins that have biotechnological importance.

BIO 441E Modeling in Biological Systems (3-0-0)

The theory of linear difference equations applied to population growth, nonlinear difference equations, applications of nonlinear difference equations to population biology, an introduction to computer models, phase-plane methods and qualitative solutions, applications of continious models to population dynamics, models for molecular events, limit cycles, oscillations, and excitable systems, an introduction to partial differential equations and diffusion in biological settings, partial differential equation models in bilogy, models for dvelopment and pattern formation in biological systems.
 
BIO 464E Microbial Genetics (3-0-0)

Mutations and genetic analysis, properties of plasmids, bacterial conjugation, bacterial transformation: natural transformation, transduction, lytic bacteriophages: genetic analysis, general transduction, phage l and lysogeny; specialized transduction, transposition and site specific recombination, global control networks in bacteria: alternative sigma factors, two component regulatory systems, sporulation, quorum-sensing, organization of microbial genomes: bacterial chromosomes.
 

        BIO 466E Developmental Biology (3-0-0)

Introduction to developmental biology, cell environments during development, cell to cell communication during development, the paracrine and the  juxtractine factors important during development, how cell death shapes life during development, model systems including vertebrates (amphibians-xenopus leavis, birds-chicken, mammals-mouse) invertebrates (the fruit fly - Drosophila melanogaster, the nematode - Caenorhhabditis elegans) plants (Arabidopsis thaliana), development of the human embriyo, cell differentiation models and mechanisms.
 

BIO 468 Current Topics in Ecology  (3-0-0)

Age and stage based population dynamics, introductory population genetics, spatial-temporal pattern dynamics of landscapes, issues concerning biodiversity and ecosystem structure and stability, quaternary paleoecology and its relevance in predicting global climate change impacts, long Term Ecological Research (LTER) sites, Biosphere 2 ‘experiment’.

 

BIO 492E Graduation Project (0-6-0)

A projects is designed on a specific in an area of molecular biology and biotechnology for individual students to carryout laboratory studies under the supervision of a faculty member. A written final report is required.